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Question.3438 - Clinical Genetics Module 3B Homework Name _________________________ This is worth 25 points. Upload to the Assignment 3B portal by the deadline. Define the following terms, 1 pt each. Type in the yellow area to automatically highlight your answers. Autosome _ Hemizygous_ Nondisjunction _ Heterogametic sex _ Lyonization _ Mosaic _ Barr body _ What is the role of the SRY gene in gender determination? Is it possible for an XX individual to have the SRY gene? What happens in that case? (3 pts) _ Discuss the phenotype of the F1 generation in this cross by Morgan. Predict the results of the F2 generation from this cross. What chromosome is the white gene on? (3 pts) _ Describe sex determination in humans (SRY), haplo-diplo system, the ZW system and the ratio system of Drosophila. 4 pts _ Color deficiency is X linked. A man who is color blind has 4 daughters. None of them are color deficient. What is the probability that his daughters are carriers (heterozygous) for color deficiency? (2 pts) _ There are 3 mechanisms discussed to compensate for ‘dosage’. What is dosage, and what are the 2 mechanisms? (4 pts) _ What gender are calico cats? What chromosome codes for color in cats? 2 pts _

Answer Below:

Clinical xxxxxxxx Module x Homework xxxx This xx worth xxxxxx Upload xx the xxxxxxxxxx B xxxxxx by xxx deadline xxxxxx the xxxxxxxxx terms xx each xxxx in xxx yellow xxxx to xxxxxxxxxxxxx highlight xxxx answers xxxxxxxx These xxx a xxxxxx of xxxxxxxxxxx that xx not x sex xxxxxxxxxx For xxxxxxx humans xxxx pairs xx chromosomes xxxxxxxxxx It xx defined xx the xxxxx of xxxxxx only xxx copy xx a xxxx or xxxxxxxxxx rather xxxx a xxxxx of xxxxxx two xxxx as xx the xxxx of xxxxx on xxx X xxxxxxxxxx in xxxxx Nondisjunction xx in xxx case xxx chromosome xx chromatids xxxxx to xxxxxxxx properly xxxxxx cell xxxxxxxx could xxxx to xx abnormal xxxxxx of xxxxxxxxxxx in xxx daughter xxxxx Heterogametic xxx Organisms xxxx as xxxxx males xxxx two xxxxxxxxx types xx sex xxxxxxxxxxx such xx XY xxxxxxxxxxx It xx a xxxxxxx where xxx of xxx two x chromosomes xx female xxxxxxx have xxxx randomly xxxxxxxxxxx during xxx early xxxxxxxxxxx in xxxxxxxxx the xxxx dosage xxxxxxx males xxx females xxxxxx It xx an xxxxxxxxxx with xxx or xxxx genetically xxxxxxxxx cell xxxxx derived xxxxxxx a xxxxxx zygote xxxxxxxxx due xx mutations xx any xxxxx changes xxxx could xxxxx during xxx time xx development xxxx body xx is xx inactivated x chromosome xxxxxx a xxxxxx cell xxxx is xxxxxxxx and xxx actively xxxxxxxxxx since xx could xx either xxxxx or xxxxx dense xxxxxxxxx in xxx nucleus xxxx is xxx role xx the xxx gene xx gender xxxxxxxxxxxxx Is xx possible xxx an xx individual xx have xxx SRY xxxx What xxxxxxx in xxxx case xxx The xxx or xxxxxxxxxxxxxxx Region x gene xxx been xxxxxxx a xxxxxxx role xx determination xx sex xx an xxxxxxxxxx This xx located xx the x chromosome xxx triggers xxx development xx testes xxxxxx the xxxxxx leading xx the xxxxxxxxxx of xxxxx hormones xx well xx the xxxxxxxxxxx of xxx male xxxxxxxxx sexual xxxxxxxxxxxxxxx However xx is xxxxxxxx for xxx XX xxxxxxxxxx for xxxxxx the xxx gene xx it xxx been xxxxxxxxxxxx from xxx Y xxxxxxxxxx to xxx of xxx X xxxxxxxxxxx referring xx as xxx XX xxxx syndrome xx the xxxxx syndrome xxxxx rare xxxxx may xxxx the xxx gene xxxxxxx the xxxxxxxxxxx of xxxxxx and xxxx secondary xxxxxx characteristics xxxxxxxx the xxxxxxxxxx may xxxxxxx an xx karyotype xxxxxxx the xxxxxxxxx of xxx F xxxxxxxxxx in xxxx cross xx Morgan xxxxxxx the xxxxxxx of xxx F xxxxxxxxxx from xxxx cross xxxx chromosome xx the xxxxx gene xx pts xxxx the xxxxx analysis xxx color xx eye xx based xx the xxxxxxxxxxxx and xx reflects xx with xxx sense xxxxx red-eye xx a xxxx type xxxxxxx the xxxxxxxxx is xxx mutant xxxx For xxxxxxxx the x generation xxxx the xxxxxxxxx F xxxxx be xxxxx genotype xx female x w xxxxxxxx of xxxx w x X x W x X x W x Red-eyed x O xxxxxxxx X x W x Red-eyed xx White xxxx Thus xxxx the xxxxx table xx could xx evaluated xxxx the xxxxxxxxxx gene xx on xxx X-chromosome xx nexus xxxx this xxx F xxxxxxx may xxxxxxxx ratio xxxx two xxxxxxx having xxxxxxx and xxxx in xxxxxxxx and xxxx has xxxxx eyes xxxxxxxx sex xxxxxxxxxxxxx in xxxxxx SRY xxxxxxxxxxx system xxx ZW xxxxxx and xxx ratio xxxxxx of xxxxxxxxxx pts xxxxx Sex xxxxxxxxxxxxx SRY xxxxxx In xxxxxx the xxx determination xxx been xxxxxxxxx governed xxxx the xxxxxxxx of xxx SRY xxxx that xx located xx the x chromosome xxx instance xx the xxx gene xx present xxxx it xxxxx regard xx as xx XY xxxxxxxxxxx similarly xxx absence xx SRY xxxx determine xx XX xxxxxxxxxx However xx rare xxxxx of xxxxxxxx the xxx gene xxxxx be xxxx evident xx the xx individual xxxxxxx to xxxx secondary xxxxxx characteristics xx female xxxxxx XX xxxxxxxxxxx Haplo-diplo xxxxxx It xx found xxxx insects xxxxxxxxx bees xxx ants xxxxx it xxxxxxxxxx the xxx based xx the xxxxxx of xxxx of xxxxxxxxxxx For xxxxxxxx haploid xxxxx have xxxx developing xxxx unfertilized xxxx whereas xxx diploid xxxxxxx develop xxxx the xxxxxxxxxx eggs xxx they xxxxxxx contain xxx sets xx chromosomes xxx ZW xxxxxx This xx found xx birds xxxx reptiles xxx even xxxxxxx fishes xxxxx it xxx been xxx counterpart xx the xx system xx the xxxxxxx with x reversed xxxxxxx For xxxxxxxx female xxxx ZW xxx chromosomes xxxxx males xxxx ZZ xxx chromosome xxxxx system xx Drosophila xxx fruit xxxxx or xxxxxxxxxx melanogaster xxxx a xxxxxx sex xxxxxxxxxxxxx system xxxxx on xxx ratio xx X xxxxxxxxxxx with xxx set xx autosomes xxxx the x ratio xxxx X x denotes xxx number xx X xxxxxxxxxxx and x denotes xxx number xx autosome xxxx In xxxx scenario xxxxxxx have xx X xxxxx of xxxxxxx males xxxx an x ratio xx Color xxxxxxxxxx is x linked x man xxx is xxxxx blind xxx daughters xxxx of xxxx are xxxxx deficient xxxx is xxx probability xxxx his xxxxxxxxx are xxxxxxxx heterozygous xxx color xxxxxxxxxx pts xxxxx blindness xxx been xxxxx on xxxxxxxx recessive xxxxx where xxx gene xxxxxxx color xxxxxxxxx have xxxx found xx the x chromosome xxx when xxx copies xx gene xxxx been xxxxxxxx for x female xxx one xxxx of xxxx is xxxxxxxx for xxxx to xxxxxxx their xxxxx The xxxxxxxxxxx factor xxx the xxxx who xx color xxxxx is xxxxxxxxx If xxx mother xx carrier xx Y xx XcXc xxxxx Blind xxx Color xxxxx X xxx Carrier xx Normal xxxxx if xxx mother xx a xxxxxxx then xxxxx is x chance xx being x carrier xxxxx chance xxxx it xxxxx be xxxxxxxxx On xxx other xxxx if xxx mother xx not x carrier xxxx Xc x X xxx Carrier xx Normal x XX xxxxxx XY xxxxxx Hence xx the xxxxxx is xxx a xxxxxxx than xxxxx is x chance xxxx of xxxxxxxx could xx carrier xxxxxxx none xx them xxxx express xxxxx blindness xxxxx are xxxxxxxxxx discussed xx compensate xxx dosage xxxx is xxxxxx and xxxx are xxx mechanisms xxx Dosage xxx been xxxxxxxx to xxx number xx gene xxxxxxxx either xxxxxxx or xxx that xxxx been xxxxxxxx by x gene xxxxxxx dosage xxxxxxxxxxxx has xxxx the xxxxxxxxx balancing xxx gene xxxxxxxxxx levels xxxxxxx the xxxxxxxxxxx with xxxxxxxxx number xx sex xxxxxxxxxxx such xx found xx humans xxx instance xx represents xxx females xxx XY xxxxxxxxxx the xxxxx in xxxxxx that xxxxx to xx equalized xxx gene xxxxxx of xxxxxxxxxx genes xxxxxxxx that xxxxxx development xxx function xx met xx this xxxxxxxx dosage xxxxxxxxxxxx is xxxxx on xxx primary xxxxxxxxxx including xxxxxxxxxxxxxx or xxxxxxxxxxx and xxxxxx compensation xxxxxxxxx DCC xx drosophila xxxxxxxxxxx in xxxxxxx have xxxx based xxxxx one x chromosome xx females xxxx been xxxxxxxxxxx for xxxxxxxxx the xxxx dosage xx the xxxxx hand xxxxxxxxx in xxxxxxxxxx is xxx where xxxxxx X xxxxxxxxxx in xxxxx have xxxx upregulated xxxxxxxx with xxxxxx for xxx X xxxxxxxxxxx within xxx females xxxx gender xxx calico xxxx What xxxxxxxxxx codes xxx color xx cats xxx Calico xxxx have xxxx always xxxxxx where xxx distinctive xxxxxx coloration xxx been xxx result xx the xxxxxxxx gene xxxx determines xxx color xx its xxx The xxxxx located xx the x chromosome xxxxxxxxxx the xxxx color xxxxxxx Here xxx different xxxxx genes xx the x chromosomes xxxxxxxxx a xxxxx and xxxxxx along xxxx a xxxxx gene xxx white xxxxxxxx has xxxx present xxxx represent xxxxx color xx the xxxxx hand xxxxx typically xxxx only xxx X xxxxxxxxxx hence xxxx could xxx be xxxxxx showcasing xxxx are xxxxxxxxx either xxxxx or xxxxxx or xxxx in xxxxxxx anomaly xxxx as xxxxxxxxxxx syndrome xxxxx showcase xxxxxxxxx color
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