Question.3445 - Clinical Genetics Module 2C Homework Name _________________________This is worth 35 points, and it will take you 1-2 hours to complete it. If it takes longer than 2 hours, ask for help. You should post your muddy points to the discussion board and help each other with ways to solve the questions. Some of the questions came from Chapter 3 questions. What is a monohybrid cross? ___ (1 pt) What is the expected genotype ratio of the progeny of a monohybrid cross? ___ (1 pt) What is the expected phenotype ratio of the progeny of a monohybrid cross? ___(1 pt) Group O is recessive to Group A blood. A couple who both have group A blood have 3 children. All of them have group O blood. Explain this. ___ (1 pt) For this family, what is the likelihood that all 3 children have group O blood? ___ (2 pt) A plant heterozygous for 3 independently assorting genes, Aa Bb Cc is self-fertilized. Among the offspring, predict the frequency of (5 pts) (a) AA BB CC individuals, ___ (b) aa bb cc individuals, ___ (c) individuals that are either AA BB CC or aa bb cc ___ (d) Aa Bb Cc individuals ___ (e) individuals that are not heterozygous for all 3 genes (this is exercise 2 on page 57 of Sunustead. If you are stuck, use it for help) ___ Evaluate the pedigree images shown below, and state where the trait is dominant, recessive or X linked. Explain your reasoning in each case, pointing out the gender of the affected individuals (6 pts) A__ B__ C__ A geneticist crossed wild, gray-colored mice with white (albino) mice. All of the progeny were gray. These progeny were intercrossed to produce to produce F2, which consisted of 198 gray and 72 white mice. Diagram the crosses (include the numbers that were given, and find the total number) ___ (2 pt) Evaluate the ratio of the progeny _____ (2 pts) Propose a hypothesis to explain these results. (This means: what are the proportions of the phenotypes you expect in a monohybrid cross) ___ (1 pt) Compare the results with the predictions of the hypothesis and state your conclusion. (This means, use Chi square analysis) ___ (4 pt). This will help, complete each blank: What is the number of gray mice you expected to get? __ White mice? __ What is the number of gray mice you observed? __ white mice? __ What is the “degrees of freedom” for this cross? __ What is the critical value for that number of degrees of freedom? __ What is your conclusion? In mice, the allele C for colored fur is dominant over the allele c for white fur, and the allele V for normal behavior is dominant over the allele v for waltzing behavior, a form of discoordination. Give the genotypes of the parents in each of the following crosses. (Hint: list the phenotypes and number of the progeny and look at their ratios. Look at the C separately from the V). Colored, normal mice mated with white, normal mice produced 29 colored, normal and 10 colored, waltzing progeny. (3 pt) _Genotypes of the parents are __ Colored, normal mice mated with colored, normal mice produced 38 colored, normal, 15 colored, waltzing, 11 white, normal and 4 white, waltzing progeny. (3 pt) _ Genotypes of the parents are ____ Colored, normal mice mated with white, waltzing mice produced 8 colored, normal, 7 colored, waltzing, 9 white, normal, and 6 white, waltzing progeny. (3 pt) _ Genotypes of the parents are ____
Answer Below:
A xxxxxxxxxx cross xxx been xxx hybrid xx two xxxxxxxxxxx having xxxxxxxxxx genotypes xxxx result xx opposite xxxxxxxxxx for x certain xxxxxxx trait xxx instance xxx cross xxxxxxx two xxxxxxxxxx traits xxxx as xxx height xx a xxx plant xx and xx is xxxxxx a xxxxxxxxxx cross xxxxx they xxx responsible xxx the xxxxxxxxxxx of xxx gene xxxx as xxxxx tall xx dwarf xx a xxx plant xxx genotypic xxxxx for xxxxxxxxxx cross xx with xxxxxxxxxx dominant xx heterozygous xx homozygous xxxxxxxxx The xxxxxxxxxx ratio xxxxxxxxxx in x monohybrid xxxxx For xxx couple xxxx both xxxxxx A xxxxx could xxxx children xx any xxxxxx has xxxxx A xxxxx and xxx three xx their xxxxxxxx have x blood xxxxx it xxxxxxxxx that xxxx the xxxxxxx are xxxxxxxxxxxx for xxx A xxxxxx and xxxx been xxxxxxxx the xxxxxxxxx O xxxxxx with xxxx For xxxxxxxx when xxxx parents xxx heterozygous xxxx could xxxxxxxxxx an x allele xx their xxxxx leading xx a xxxxx with xx O xxxxx type xx genotype xxxxx on xxx analysis xx Punnett xxxxxx if xxxx the xxxxxxx are xx then xxxxx is x chance xx their xxxxx inheriting xxx O xxxxxx genes xxxx A x A xx AO x AO xx The xxxxx table xxxxx describes x genotypic xxxxx where xx homozygous xxxxxxxx is xx heterozygous xxxxxxxxx and xxxxxx of xxxxxxxxxx recessive xxxxxxxxxx O xxxxx group xxxxx the xxxxx assort xxxxxxxxxxxxx an xxxxxxxxxxx assortment xx required xx analyze xxxx one xx a xxxx and xxxxxx the xxxxxxx for xxxx of xxxx In xxxxx to xxxxxxxx the xxxxxxxxx of xx BB xx individuals xxxxxxxxxxx of xx nbsp xxxx nbsp xxxx nbsp xx x xx results xx frac xx Probability xx BB xxxx nbsp xxxx nbsp xxxx Bb x Bb xxxxxxx in xxxx BB xxxxxxxxxxx of xx nbsp xxxx nbsp xxxx nbsp xx x xx results xx frac xx Thus xxx frequency xx AA xx CC xxxxxxxxx could xx frac x frac x frac xxxxxxxxx the xxxxxxxxx of xx bb xx individuals xxxxx be xxxx In xxxxx to xxxxxx the xxxxxxxxx of xxxxxxxxx that xxxxx be xxxxxx triple xxxxxxxx homozygous xx triple xxxxxxxxx homozygotes xxxx mutually xxxx exclusive xxxxxxx hence xxxx the xxx of xxx results xx a xxx b xx could xxx In xxxxx to xxxxxx the xxxxxxxxx of xxxxxxxxx that xxxx triple xxxxxxxxxxxxx again xx multiply xxxxxxxxxxxxx Hence xxx each xxxx the xxxxxxxxx of xxxxxxxxxxxx should xx frac x frac x frac xxxxxxxxx that xxxx been xxx heterozygous xxx all xxxxx genes xxxxx with x frequency xxxx is xxx minus xxx frequency xxxxxxxxxx in x as x The xxxxx pedigree xxxxx shows xxxx some xx the xxxxx have xxxx showcasing xx X-linked xxxxxxxxx pattern xxxx is xxxx evident xx the xxxxx of xxx family xx the xxxxxx correspondence xxxxxxx the xxxxxxxxx X-linked xxxxxxxxx inheritance xxx second xxxxx showcases x recessive xxxxx that xxx occur xx individuals xxxxx parents xxxx been xxx affected xxxxx rare xxxxxxxxx traits xxx most xxxxxx to xxxxxx in x pedigree xxxx spouses xxxx been xxxxxxx to xxxx other xxx third xxxxx showcases xxx inheritance xx hereditary xxxxxxxxxxxxx colorectal xxxxxx where x dominant xxxxxxxx has xxxx affecting xxx family xxxxxxx from xxxx scenario x Diagram xxx crosses xxxxxxx cross xx Wild xxxx mice xx X xxxxx albino xxxx gg xxxx G x g xx Gg x Gg xx Thus xxx F xxxxxxxxx are xxxx Gg x intercross xxxx nbsp xxxx nbsp xxxx nbsp xxxx nbsp xxxx nbsp xxxx gt x gray xx X x gray xx nbsp x G x GG xx g xx gg xxxx here xxx phenotypic xxxxx is xxxxx of xxx progeny xxx gray xxxx whereas xx the xxxxxxx is xxx white xxxxxx mice xxxxx Gray xxxx White xxxx Total x The xxxxx of xxxxxxx hence xxxxxxxxx thatTotal xxxxxxx Gray xxxx White xxxx Ratio xxxxxxxxxxxxx ranging xx C xxxxxxxxxx The xxxx G xxxxxx has xxxx dominant xxxx the xxxxx g xxxxxxx comparing xxx results xxxx predictions xx the xxxxxxxxxx using xxxxxxxxxx analysis xxxxxxxx numbers xxxxxxxx ratio xxxxx progeny xxxxxxxx numbers xx gray xxxx frac x Expected xxxxxxx of xxxxx mice xxxx x xxxxxxxx numbersObserved xxxx mice xxxxxxxx white xxxx Degrees xx freedom xx Number xx categories- xxxxxx of xxxxxxxxxx wild xxxx mice xxx white xxxxxx mice xx - xxxx for xx at x significance xxxxx of xxx critical xxxxx from xxx chi-square xxxxxxxxxxxx table xx Thus xxxxxxx the xxxxxx on xxxx evaluates xxxx for xxxx mice xxxx Thus xxxxxxx the xxxxxx on xxxx evaluates xxxx for xxxxx mice xxxx Thus xxx calculated xxxxxxxxxx lower xxxx the xxxxxxxx value xxxxxxxxx through xxx significance xxxxx is xxxx it xxx been xxxxx that xxx calculated xxxxxxxxxx value xxx been xxxx than xxx critical xxxxx failing xx reject xxx null xxxxxxxxxx Although xxxxxxxx results xxxx been xxxxxxxxxx with xxxxxxxx data x phenotypic xxxxx is xxxxx Thus xx is xxxxxx that xxx ratio xx phenotypic xxxxxxxxxxx is xxxxxxxx by xxxxxxxxx inheritance xxxxxxxxxx the xxxx hypothesis x From xxx problem xx could xx evaluated xxxx nbsp xxxx nbsp xxxx nbsp xxxx nbsp xxxx nbsp xxxx nbsp xxxxxxx and xxxxxx CV xxxx nbsp xxxx nbsp xxxx nbsp xxxx nbsp xxxx nbsp xxxx Colored xxx waltzing xx From xxx discussion xx has xxxx found xxxx C xx dominant xxxx c xxx V xx dominant xxxx v xxxx the xxxxxxx could xx either xxxxxxxxxxxx or xxxxxxxxxx such xxx Colored xxxxxx CcVv xx CCVVAnd x nbsp xxxxx Normal xxxx or xxxxxx has xxxx found xxxx parent x CcVv xxx P xxxxx Phenotypes xx the xxxxxxxxx include xxxxxxx and xxxxxx CV xxxxxxx and xxxxxxxx Cv xxxxx and xxxxxx cv xxxxx and xxxxxxxx Cv xx could xx evident xxxx all xxx progenies xxxx been xxxxxxx heterozygous xxxxxx where xxxx could xxxxxxx them xxxx if xxx parents xxxx been xxxxxx heterozygous xxxx as xxxx leading xx the xxxxxxxxx nbsp xx Cv xx cv xx CCVV xxxxxxx normal xxxx Colored xxxxxx CcVV xxxxxxx normal xxxx Colored xxxxxx Cv xxxx Colored xxxxxx CCvv xxxxxxx waltzing xxxx Colored xxxxxx Ccvv xxxxxxx waltzing xx CcVV xxxxxxx normal xxxx Colored xxxxxx ccVV xxxxx normal xxxx White xxxxxx cv xxxx Colored xxxxxx Ccvv xxxxxxx waltzing xxxx White xxxxxx ccvv xxxxx waltzing xxxx C xxxx the xxxxxxx it xxxxx be xxxxxxx that xxxx colored xxxxxx mice x V xxxxx with xxxxx waltzing xxxx produced xxxxxxx and xxxxxx CV xxxxxxx and xxxxxxxx Cv xxxxx and xxxxxx cV xxxxx and xxxxxxxx cv xxxx the xxxxxxx for xxx above xxxxxxx would xx heterozygous xxxxxxx normal xxxx CcVv xxx homozygous xxxxxxxxx white xxxxxxxx ccvv xxxx nbsp xxxxxxxxxxxxxxxxx D x amp xxxxxxx M x Principles xx genetics xxxx Wiley xxx SonsMore Articles From Genetics
.ico)
.ico)
.ico)
.ico)
