Question.3445 - Clinical Genetics Module 2C Homework Name _________________________This is worth 35 points, and it will take you 1-2 hours to complete it. If it takes longer than 2 hours, ask for help. You should post your muddy points to the discussion board and help each other with ways to solve the questions. Some of the questions came from Chapter 3 questions. What is a monohybrid cross? ___ (1 pt) What is the expected genotype ratio of the progeny of a monohybrid cross? ___ (1 pt) What is the expected phenotype ratio of the progeny of a monohybrid cross? ___(1 pt) Group O is recessive to Group A blood. A couple who both have group A blood have 3 children. All of them have group O blood. Explain this. ___ (1 pt) For this family, what is the likelihood that all 3 children have group O blood? ___ (2 pt) A plant heterozygous for 3 independently assorting genes, Aa Bb Cc is self-fertilized. Among the offspring, predict the frequency of (5 pts) (a) AA BB CC individuals, ___ (b) aa bb cc individuals, ___ (c) individuals that are either AA BB CC or aa bb cc ___ (d) Aa Bb Cc individuals ___ (e) individuals that are not heterozygous for all 3 genes (this is exercise 2 on page 57 of Sunustead. If you are stuck, use it for help) ___ Evaluate the pedigree images shown below, and state where the trait is dominant, recessive or X linked. Explain your reasoning in each case, pointing out the gender of the affected individuals (6 pts) A__ B__ C__ A geneticist crossed wild, gray-colored mice with white (albino) mice. All of the progeny were gray. These progeny were intercrossed to produce to produce F2, which consisted of 198 gray and 72 white mice. Diagram the crosses (include the numbers that were given, and find the total number) ___ (2 pt) Evaluate the ratio of the progeny _____ (2 pts) Propose a hypothesis to explain these results. (This means: what are the proportions of the phenotypes you expect in a monohybrid cross) ___ (1 pt) Compare the results with the predictions of the hypothesis and state your conclusion. (This means, use Chi square analysis) ___ (4 pt). This will help, complete each blank: What is the number of gray mice you expected to get? __ White mice? __ What is the number of gray mice you observed? __ white mice? __ What is the “degrees of freedom” for this cross? __ What is the critical value for that number of degrees of freedom? __ What is your conclusion? In mice, the allele C for colored fur is dominant over the allele c for white fur, and the allele V for normal behavior is dominant over the allele v for waltzing behavior, a form of discoordination. Give the genotypes of the parents in each of the following crosses. (Hint: list the phenotypes and number of the progeny and look at their ratios. Look at the C separately from the V). Colored, normal mice mated with white, normal mice produced 29 colored, normal and 10 colored, waltzing progeny. (3 pt) _Genotypes of the parents are __ Colored, normal mice mated with colored, normal mice produced 38 colored, normal, 15 colored, waltzing, 11 white, normal and 4 white, waltzing progeny. (3 pt) _ Genotypes of the parents are ____ Colored, normal mice mated with white, waltzing mice produced 8 colored, normal, 7 colored, waltzing, 9 white, normal, and 6 white, waltzing progeny. (3 pt) _ Genotypes of the parents are ____
Answer Below:
A xxxxxxxxxx cross xxx been xxx hybrid xx two xxxxxxxxxxx having xxxxxxxxxx genotypes xxxx result xx opposite xxxxxxxxxx for x certain xxxxxxx trait xxx instance xxx cross xxxxxxx two xxxxxxxxxx traits xxxx as xxx height xx a xxx plant xx and xx is xxxxxx a xxxxxxxxxx cross xxxxx they xxx responsible xxx the xxxxxxxxxxx of xxx gene xxxx as xxxxx tall xx dwarf xx a xxx plant xxx genotypic xxxxx for xxxxxxxxxx cross xx with xxxxxxxxxx dominant xx heterozygous xx homozygous xxxxxxxxx The xxxxxxxxxx ratio xxxxxxxxxx in x monohybrid xxxxx For xxx couple xxxx both xxxxxx A xxxxx could xxxx children xx any xxxxxx has xxxxx A xxxxx and xxx three xx their xxxxxxxx have x blood xxxxx it xxxxxxxxx that xxxx the xxxxxxx are xxxxxxxxxxxx for xxx A xxxxxx and xxxx been xxxxxxxx the xxxxxxxxx O xxxxxx with xxxx For xxxxxxxx when xxxx parents xxx heterozygous xxxx could xxxxxxxxxx an x allele xx their xxxxx leading xx a xxxxx with xx O xxxxx type xx genotype xxxxx on xxx analysis xx Punnett xxxxxx if xxxx the xxxxxxx are xx then xxxxx is x chance xx their xxxxx inheriting xxx O xxxxxx genes x O x AA xx O xx OO xxx above xxxxx hence xxxxxxxxx a xxxxxxxxx ratio xxxxx is xxxxxxxxxx dominant xx of xxxxxxxxxxxx dominance xxx chance xx homozygous xxxxxxxxx showcasing x blood xxxxx Since xxx genes xxxxxx independently xx appropriate xxxxxxxxxx is xxxxxxxx to xxxxxxx them xxx at x time xxx obtain xxx answers xxx each xx them xx order xx evaluate xxx frequency xx AA xx CC xxxxxxxxxxx Probability xx AA xx x xx results xx AA xxxxxxxxxxx of xx Bb x Bb xxxxxxx in xx Probability xx CC xx x xx results xx CC xxxx the xxxxxxxxx of xx BB xx offspring xxxxx be x x xxxxxxxxx the xxxxxxxxx of xx bb xx individuals xxxxx be xxxx In xxxxx to xxxxxx the xxxxxxxxx of xxxxxxxxx that xxxxx be xxxxxx triple xxxxxxxx homozygous xx triple xxxxxxxxx homozygotes xxxx mutually xxxx exclusive xxxxxxx hence xxxx the xxx of xxx results xx a xxx b xx could xxx In xxxxx to xxxxxx the xxxxxxxxx of xxxxxxxxx that xxxx triple xxxxxxxxxxxxx again xx multiply xxxxxxxxxxxxx Hence xxx each xxxx the xxxxxxxxx of xxxxxxxxxxxx should xx x x Offspring xxxx have xxxx not xxxxxxxxxxxx for xxx three xxxxx occur xxxx a xxxxxxxxx that xx one xxxxx the xxxxxxxxx calculated xx d xx - xxx first xxxxxxxx image xxxxx that xxxx of xxx males xxxx been xxxxxxxxxx an xxxxxxxx recessive xxxxxxx that xx only xxxxxxx in xxx males xx the xxxxxx if xxx female xxxxxxxxxxxxxx carries xxx recessive xxxxxxxx recessive xxxxxxxxxxx The xxxxxx image xxxxxxxxx a xxxxxxxxx trait xxxx may xxxxx in xxxxxxxxxxx whose xxxxxxx have xxxx not xxxxxxxx These xxxx recessive xxxxxx are xxxx likely xx appear xx a xxxxxxxx when xxxxxxx have xxxx related xx each xxxxx The xxxxx image xxxxxxxxx the xxxxxxxxxxx of xxxxxxxxxx non-polyploid xxxxxxxxxx cancer xxxxx a xxxxxxxx mutation xxx been xxxxxxxxx the xxxxxx members xxxx each xxxxxxxx A xxxxxxx the xxxxxxx Initial xxxxx Wild xxxx mice xx X xxxxx albino xxxx gg x G x Gg xx g xx Gg xxxx all x progenies xxx gray xx F xxxxxxxxxx F xxxx Gg x F xxxx Gg x G x GG xx g xx gg xxxx here xxx phenotypic xxxxx is xxxxx of xxx progeny xxx gray xxxx whereas xx the xxxxxxx is xxx white xxxxxx mice xxxxx Gray xxxx White xxxx Total x The xxxxx of xxxxxxx hence xxxxxxxxx thatTotal xxxxxxx Gray xxxx White xxxx Ratio xxxxxxxxxxxxx ranging xx C xxxxxxxxxx The xxxx G xxxxxx has xxxx dominant xxxx the xxxxx g xxxxxxx comparing xxx results xxxx predictions xx the xxxxxxxxxx using xxxxxxxxxx analysis xxxxxxxx numbers xxxxxxxx ratio xxxxx progeny xxxxxxxx numbers xx gray xxxx x xxxxxxxx numbers xx white xxxx x xxxxxxxx numbersObserved xxxx mice xxxxxxxx white xxxx Degrees xx freedom xx Number xx categories- xxxxxx of xxxxxxxxxx wild xxxx mice xxxxx albino xxxx df x Thus xxx df xx a xxxxxxxxxxxx level xx the xxxxxxxx value xxxx the xxxxxxxxxx distribution xxxxx is xxxx putting xxx values xx this xxxxxxxxx that xxx gray xxxx Thus xxxxxxx the xxxxxx on xxxx evaluates xxxx for xxxxx mice xxxx the xxxxxxxxxx chi-square xxxxx than xxx critical xxxxx estimated xxxxxxx the xxxxxxxxxxxx level xx Thus xx has xxxx found xxxx the xxxxxxxxxx chi-square xxxxx has xxxx less xxxx the xxxxxxxx value xxxxxxx to xxxxxx the xxxx hypothesis xxxxxxxx observed xxxxxxx have xxxx correlated xxxx existing xxxx a xxxxxxxxxx ratio xx found xxxx it xx proved xxxx the xxxxx of xxxxxxxxxx development xx followed xx Mendelian xxxxxxxxxxx justifying xxx null xxxxxxxxxx A xxxx the xxxxxxx it xxxxx be xxxxxxxxx that xxxxxxx and xxxxxx CV xxxxxxx and xxxxxxxx Cv xxxx the xxxxxxxxxx it xxx been xxxxx that x is xxxxxxxx over x and x is xxxxxxxx over x Here xxx parents xxxxx be xxxxxx heterozygous xx homozygous xxxx asP xxxxxxx normal xxxx or xxxxxxx P xxxxx Normal xxxx or xxxxxx has xxxx found xxxx parent x CcVv xxx P xxxxx Phenotypes xx the xxxxxxxxx include xxxxxxx and xxxxxx CV xxxxxxx and xxxxxxxx Cv xxxxx and xxxxxx cv xxxxx and xxxxxxxx Cv xx could xx evident xxxx all xxx progenies xxxx been xxxxxxx heterozygous xxxxxx where xxxx could xxxxxxx them xxxx if xxx parents xxxx been xxxxxx heterozygous xxxx as xxxx leading xx the xxxxxxxxx CV xx cV xx CV xxxx Colored xxxxxx CCVv xxxxxxx normal xxxx Colored xxxxxx CcVv xxxxxxx normal xx CCVv xxxxxxx normal xxxx Colored xxxxxxxx CcVv xxxxxxx normal xxxx Colored xxxxxxxx cV xxxx Colored xxxxxx CcVv xxxxxxx normal xxxx White xxxxxx ccVv xxxxx normal xx CcVv xxxxxxx normal xxxx Colored xxxxxxxx ccVv xxxxx normal xxxx White xxxxxxxx C xxxx the xxxxxxx it xxxxx be xxxxxxx that xxxx colored xxxxxx mice x V xxxxx with xxxxx waltzing xxxx produced xxxxxxx and xxxxxx CV xxxxxxx and xxxxxxxx Cv xxxxx and xxxxxx cV xxxxx and xxxxxxxx cv xxxx the xxxxxxx for xxx above xxxxxxx would xx heterozygous xxxxxxx normal xxxx CcVv xxx homozygous xxxxxxxxx white xxxxxxxx ccvv xxxxxxxxxxxxxxxxx D x Simmons x J xxxxxxxxxx of xxxxxxxx John xxxxx SonsMore Articles From Genetics
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